HDAC1 regulates pluripotency and lineage specific transcriptional networks in embryonic and trophoblast stem cells
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چکیده
منابع مشابه
HDAC1 regulates pluripotency and lineage specific transcriptional networks in embryonic and trophoblast stem cells
Epigenetic regulation of gene expression is important in maintaining self-renewal of embryonic stem (ES) and trophoblast stem (TS) cells. Histone deacetylases (HDACs) negatively control histone acetylation by removing covalent acetylation marks from histone tails. Because histone acetylation is a known mark for active transcription, HDACs presumably associate with inactive genes. Here, we used ...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2011
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gkr1151